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Displaying results 5301 - 5310 of 9322 in total
  1. Drug

    MKC1106-PP

    go.drugbank.com/drugs/DB06030
    Experimental

    The plasmid portion is a recombinant plasmid expressing segments of the 2 target antigens, PRAME and PSMA. … MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM.

  2. Drug

    Brifentanil

    go.drugbank.com/drugs/DB09172
    ExperimentalIllicit

    The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable itching and respiratory depression. … This drug is classified as an opioid analgesic and was developed in the early 1990s.

  3. Drug

    Chikungunya virus Senegal strain 37997 envelope protein E1

    go.drugbank.com/drugs/DB21767
    ApprovedInvestigational

    One of three components of a recombinant Chikungunya virus vaccine called Vimkunya.

  4. Drug

    Ranirestat

    go.drugbank.com/drugs/DB05327
    Investigational

    It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.

  5. Drug

    AS1409

    go.drugbank.com/drugs/DB05182
    Investigational

    One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma.

  6. Drug

    Tetrathiomolybdate

    go.drugbank.com/drugs/DB05088
    Investigational

    It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body. … COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease.

  7. Drug

    Simurosertib

    go.drugbank.com/drugs/DB16330
    Investigational

    Simurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal

  8. Drug

    Foslevodopa

    go.drugbank.com/drugs/DB16683
    Approved

    Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants

  9. Drug

    BMS-986104

    go.drugbank.com/drugs/DB15214
    Investigational

    BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

  10. Drug

    Ertumaxomab

    go.drugbank.com/drugs/DB18923
    Investigational

    Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy).