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Displaying results 5331 - 5340 of 10000 in total
  1. Drug

    Camrelizumab

    go.drugbank.com/drugs/DB14776
    Investigational

    Camrelizumab is under investigation in clinical trial NCT03417895 (SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy).

  2. Drug

    Selodenoson

    go.drugbank.com/drugs/DB16325
    Investigational

    Selodenoson is under investigation in clinical trial NCT00040001 (Safety and Efficacy Study of an A1-adenosine Receptor Agonist to Slow Heart Rate in Atrial Fibrillation).

  3. Drug

    Lovotibeglogene autotemcel

    go.drugbank.com/drugs/DB18680
    ApprovedInvestigational

    [A262736,L49256] On December 8, 2023, lovotibeglogene autotemcel was approved by the FDA under the brand name Lyfgenia for the treatment of sickle cell disease (SCD) in patients ages 12 and older who … [L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients

  4. Drug

    Talacotuzumab

    go.drugbank.com/drugs/DB14796
    Investigational

    It is under investigation in clinical trial NCT01632852 (A Study of CSL362 in Patients With CD123+ Acute Myeloid Leukemia Currently in Remission). … Talacotuzumab is an IgG1 monoclonal antibody directed toward the IL3 receptor α–subunit, also known as CD123.

  5. Drug

    ZEN-3694

    go.drugbank.com/drugs/DB22031
    Investigational

    ZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).

    Synonyms: BETi ZEN-3694
  6. Drug

    Roledumab

    go.drugbank.com/drugs/DB16317
    Investigational

    Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).

  7. Drug

    Tesnatilimab

    go.drugbank.com/drugs/DB16377
    Investigational

    Tesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).

  8. Drug

    Isatin

    go.drugbank.com/drugs/DB02095
    Experimental

    Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. … The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.

  9. Drug

    Virus Specific T-Cell

    go.drugbank.com/drugs/DB15735
    Investigational

    These T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. … In some cases, the cells are created from blood samples of patients who have recovered from viral infections.

  10. Drug

    PF-05212377

    go.drugbank.com/drugs/DB16044
    Investigational

    on Donepezil). … PF-05212377 is under investigation in clinical trial NCT01712074 (Study Evaluating Thesafety and Efficacy of PF-05212377 or Placebo in Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms