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Tesnatilimab
go.drugbank.com/drugs/DB16377InvestigationalTesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).
ZEN-3694
go.drugbank.com/drugs/DB22031InvestigationalZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).
Synonyms: BETi ZEN-3694TM5614
go.drugbank.com/drugs/DB16516InvestigationalAn animal study in mice fed a fast-food diet with TM5614 treatment showed improved metabolic measurements and reduced liver steatosis[L31673,L31678]. … Further investigation of this compound is underway, including an exploratry Phase II study for its efficacy and safety for high-risk hospitalized patients with severe COVID-19 pneumonia[L31688].
NLX-P101
go.drugbank.com/drugs/DB05924Experimentalwhich is overactive in patients with Parkinson’s disease. … NLX-P101 is being evaluated as a therapeutic drug when injected into this deep brain structure that is known to function abnormally in Parkinson’s patients.
Bremzalerbart
go.drugbank.com/drugs/DB19417InvestigationalBremzalerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Atisnolerbart
go.drugbank.com/drugs/DB19418InvestigationalAtisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
N-chlorotaurine
go.drugbank.com/drugs/DB06633ExperimentalN-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase.
Synonyms: N-chlorotaurine, N-monochlorotaurineAcetylcysteine zidrimer
go.drugbank.com/drugs/DB16496InvestigationalSynonyms: Dendrimer N-acetyl-cysteine