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Ramipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalIt is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular
Synonyms: (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acidMixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, Trinomia 100 mg/20 mg/5 mg HartkapselnPapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.
Categories: Heterocyclic Compounds, 2-Ring, Drugs Used in Erectile DysfunctionProducts: PAPAVERINE HCL 60 MG TABLET, 20 ADET, PAPAVERİN HCL GALEN 40 MG/2 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 10 AMPULGadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigational(From Martindale, The Extra Pharmacopoeia, 30th ed, p706) … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.
Categories: Compounds used in a research, industrial, or household settingProducts: MAGNEVIST FLAKON, 20 ML, MAGNEVIST FLAKON, 10 MLEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.[L12975] … Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].
Synonyms: (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane, L-erythro-2-(Methylamino)-1-phenylpropan-1-olMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, COPHADYL-E COUGH LINCTUSTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … [A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics
Synonyms: O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamineMixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, TOBRAMICINA E DESAMETASONE EGKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigational[A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.
Mixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MG, Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2%Categories: 14-alpha Demethylase InhibitorsRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingInternational brands: Risperidal M-TabFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449] … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart
Categories: Heterocyclic Compounds, 2-RingProducts: KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADETFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalFosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals
Mixtures: MONOPRIL PLUS 10 MG/12.5 MG TABLET, 28 ADET, MONOPRIL PLUS 20 MG/12.5 MG TABLET, 28 ADETCategories: Agents Acting on the Renin-Angiotensin SystemSennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalSennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label]. It is a weaker laxative than bisacodyl or castor oil[A177092].
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Sennosides 8.6 Mg and Docusate Sodium 50 Mg TabletsProducts: X-M 20 MG 40 TABLET, ROHA LAX 20 MG/5 ML GRANÜL, 150 ML