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Dovitinib
go.drugbank.com/drugs/DB05928InvestigationalDovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis.
Tusamitamab ravtansine
go.drugbank.com/drugs/DB17448InvestigationalTusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).
Crefmirlimab
go.drugbank.com/drugs/DB17577InvestigationalCrefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells)PYX-201
go.drugbank.com/drugs/DB18382InvestigationalPYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.
Pemtumomab
go.drugbank.com/drugs/DB18563ExperimentalPemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Synonyms: Murine MAb to polymorphic epithelial mucin, human milk fat globule 1Fallypride F-18
go.drugbank.com/drugs/DB19254InvestigationalFallypride F-18 is under investigation in clinical trial NCT00846040 (Reduced Carbohydrate Versus Fat in Obese Subjects).
Pifusertib
go.drugbank.com/drugs/DB15054InvestigationalTAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).
REN-850
go.drugbank.com/drugs/DB05912ExperimentalREN-850 is an oral drug for multiple sclerosis which is in Phase I of clinical trials.
D-Phenylalanine
go.drugbank.com/drugs/DB02556ExperimentalAn essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem]
Renzapride
go.drugbank.com/drugs/DB04917InvestigationalIt has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK.