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Osanetant
go.drugbank.com/drugs/DB04872InvestigationalThis follows an earlier decision to discontinue development of eplivanserin for schizophrenia. … In a review of its R&D portfolio, the company announced in August 2005 that it would cease any further development of osanetant.
C11-12 isoparaffin
go.drugbank.com/drugs/DB11329ApprovedC11-12 isoparaffin is a mixture of branched chain hydrocarbons with 11C or 12C's in the alkyl chain. It is found in cosmetic and personal care products as solvents or skin conditioning agent.
TT 173
go.drugbank.com/drugs/DB17717InvestigationalTT 173 is a Modified Human Tissue Factor currently being investigated to treat bleeding disorders such as hemophilia and von Willebrand disease, as well as bleeding episodes in cutaneous injuries or dental
Inarigivir soproxil
go.drugbank.com/drugs/DB15063InvestigationalInarigivir soproxil is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic
Foscarbidopa
go.drugbank.com/drugs/DB16171ApprovedFoscarbidopa is under investigation in clinical trial NCT04379050 (Extension Study to Evaluate Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Adult
Octopamine
go.drugbank.com/drugs/DB13251ExperimentalOctopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.
1-Deoxy-D-xylulose 5-phosphate
go.drugbank.com/drugs/DB02496Experimentalin the non-mevalonate pathway. … This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.
Icalcaprant
go.drugbank.com/drugs/DB21651InvestigationalThe usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist. … Icalcaprant is under investigation in clinical trial NCT06696755 (A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
OTL-201
go.drugbank.com/drugs/DB17652ExperimentalIt consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.[L45973] … OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA).
2-hydroxy-7-methoxy-5-methyl-naphthalene-1-carboxylic acid meso-2,5-dihydroxy-cyclopent-3-enyl ester
go.drugbank.com/drugs/DB08261ExperimentalThis drug targets the protein neocarzinostatin. … This compound belongs to the naphthalenecarboxylic acids and derivatives. These are compounds containing a napthalene moiety with a ring carbon which bears a carboxylic acid group or a derivative.