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SAB-185
go.drugbank.com/drugs/DB16491InvestigationalSynonyms: HUMAN IGG POLYCLONAL ANTIBODY DERIVED FROM PLASMA OF TRANSCHROMOSOMAL BOVINE TARGETED TO THE SPIKE PROTEIN OF SARS COV-2Categories: Experimental Unapproved Treatments for COVID-19Trafermin
go.drugbank.com/drugs/DB06244InvestigationalCategories: Preparations for Treatment of Wounds and UlcersSodium feredetate
go.drugbank.com/drugs/DB13381ApprovedCategories: Compounds used in a research, industrial, or household settingAlipogene tiparvovec
go.drugbank.com/drugs/DB13521ApprovedIt is being investigated for the treatment of lipoprotein lipase (LPL) deficiency.[A259796, A259801, A259806, A259811] … Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers the Ser(447)X variant of the human lipoprotein lipase (LPL) gene.
Omapatrilat
go.drugbank.com/drugs/DB00886ExperimentalThis drug from BMS was not approved by the FDA due to angioedema safety concerns. … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling.
Categories: Agents Acting on the Renin-Angiotensin SystemPimagedine
go.drugbank.com/drugs/DB05383InvestigationalPimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease. … It is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies.
Radotinib
go.drugbank.com/drugs/DB12323InvestigationalRadotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.
Abdavomeran
go.drugbank.com/drugs/DB15695Investigational[L15012] The modRNA is formulated in lipid nanoparticles for delivery via intramuscular injection. … BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.
Categories: Experimental Unapproved Treatments for COVID-19Irsogladine
go.drugbank.com/drugs/DB13056InvestigationalIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Categories: Compounds used in a research, industrial, or household setting, Drugs for Acid Related DisordersBL-1020
go.drugbank.com/drugs/DB05687InvestigationalBL-1020 is a first in class novel compound for the treatment of schizophrenia. It is being developed by BioLineRx (BioLine).