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MEDI6012
go.drugbank.com/drugs/DB14833InvestigationalRecombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction
Oxyphenisatin acetate
go.drugbank.com/drugs/DB14627ApprovedWithdrawnOxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]
Categories: Heterocyclic Compounds, 2-RingMelanoma antigen recognized by T-cells 1
go.drugbank.com/drugs/DB15081InvestigationalMelanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery
Synonyms: Melanoma antigen recognized by T-cells 1Indium In-111 imciromab pentetate
go.drugbank.com/drugs/DB09339ApprovedWithdrawnIndium In-111 imciromab pentetate is a mouse monoclonal antibody labelled with the radioisotope Indium-111 which was used for cardiac imaging under the trade name Myoscint, but was withdrawn in 1993.
MBT-0312
go.drugbank.com/drugs/DB05880ExperimentalMediGene's newly acquired drug candidates MBT-0312 aim at a novel method of cancer therapy by "starving out" tumors.
Pabinafusp alfa
go.drugbank.com/drugs/DB15633InvestigationalPabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Synonyms: -2-SULFATASE, DISULFIDE WITH HUMAN-MUS MUSCULUS MONO, Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa:Uliledlimab
go.drugbank.com/drugs/DB16675InvestigationalUliledlimab is under investigation in clinical trial NCT04322006 (A Phase I/II Study of TJ004309 for Advanced Solid Tumor).
Toll-like receptor 9
go.drugbank.com/drugs/DB15320InvestigationalToll-like receptor 9 is under investigation in clinical trial NCT03007732 (Pembrolizumab in Combination With Intratumoral SD-101 Therapy).
Synonyms: Toll-like receptor 9Categories: Toll-Like Receptor 9, agonistsSaredutant
go.drugbank.com/drugs/DB06660InvestigationalSaredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.
Categories: Heterocyclic Compounds, 1-Ring, Receptors, Neurokinin-2, antagonists & inhibitorsDantrolene
go.drugbank.com/drugs/DB01219ApprovedInvestigationalChemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Synonyms: 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoinCategories: Heterocyclic Compounds, 1-Ring