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VPM4001
go.drugbank.com/drugs/DB05089ExperimentalVPM4001 is an allogeneic vaccine for treatment of prostate carcinoma. … It consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ).
Rocatinlimab
go.drugbank.com/drugs/DB18809InvestigationalRocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. … In clinical trials, it has shown significant efficacy and safety compared to a placebo.
Cixutumumab
go.drugbank.com/drugs/DB12250InvestigationalCixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of tumour types.
Torcetrapib
go.drugbank.com/drugs/DB06281InvestigationalTorcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination
Iron protein succinylate
go.drugbank.com/drugs/DB11209ApprovedMixtures: KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK., KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK.Seliciclib
go.drugbank.com/drugs/DB06195InvestigationalDeveloped by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation … R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated
Alipogene tiparvovec
go.drugbank.com/drugs/DB13521ApprovedIt is being investigated for the treatment of lipoprotein lipase (LPL) deficiency.[A259796, A259801, A259806, A259811]
Vitex agnus-castus fruit extract
go.drugbank.com/drugs/DB13193InvestigationalThe main mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and
Mixtures: Menopause Relief for WomenS-40503
go.drugbank.com/drugs/DB13938ExperimentalS-40503 is an investigational selective androgen receptor modulator (SARM) developed for the treatment of osteoporosis by the Japanese company Kaken Pharmaceuticals.
AAV-dXIAP
go.drugbank.com/drugs/DB17880ExperimentalAAV-dXIAP is a recombinant adeno-associated virus-encoded gene for X-linked mammalian inhibitor of apoptosis protein (XIAP) developed by Neurologix.