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Displaying results 5661 - 5670 of 10000 in total
  1. Drug

    Levcromakalim

    go.drugbank.com/drugs/DB21154
    Investigational

    Levcromakalim has a monoisotopic molecular weight of 286.13 Da. … Levcromakalim is under investigation in clinical trial NCT04853797 (Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)).

  2. Drug

    Edotecarin

    go.drugbank.com/drugs/DB04882
    Investigational

    It is member of the class of compounds called indolocarbazoles.

  3. Drug

    Hyperforin

    go.drugbank.com/drugs/DB01892
    InvestigationalNutraceutical

    One of the most important members of this family, due to its medical properties, is _Hypericum perforatum_, also known as St John's wort. … Hyperforin is a phytochemical generated by the plants of the Hypericum family.

  4. Drug

    PRTX-100

    go.drugbank.com/drugs/DB05947
    Investigational

    PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases … These binding interactions enable the compound to modulate the function of these cells and restore the balance of the immune system.

  5. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1). … It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation).

  6. Drug

    Mevidalen

    go.drugbank.com/drugs/DB19034
    Investigational

    Mevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or

  7. Drug

    Londamocitinib

    go.drugbank.com/drugs/DB19190
    Investigational

    Londamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high

  8. Drug

    OXI-4503

    go.drugbank.com/drugs/DB05143
    Investigational

    Preclinical studies have demonstrated that OXI-4503 has (i) single-agent activity against a range of xenograft tumor models; and (ii) synergistic or additive effects when incorporated in various combination … metabolized by oxidative enzymes (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to an orthoquinone chemical species that has direct cytotoxic effects on

  9. Drug

    DP-b99

    go.drugbank.com/drugs/DB05820
    Investigational

    of stroke, head trauma and neurological damage associated with coronary artery bypass graft. … DP-b99 is a newly developed lipophilic, cell permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment

  10. Drug

    VSF-173

    go.drugbank.com/drugs/DB05753
    Investigational

    It is an oral compound that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a stimulant effect. … It is developed for the treatment of excessive sleepiness. Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive sleepiness.