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Pimodivir
go.drugbank.com/drugs/DB14974InvestigationalPimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
RO-6870810
go.drugbank.com/drugs/DB15151InvestigationalRO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Synonyms: BET INHIBITOR TEN-010, 2-[(4S)-6-(4-chlorophenyl)-1,7,8-trimethylthiophenol[3,2-f]1,2,4-triazolo[4,3-a]1,4-diazepin-4-yl]-N-[3-(4-methylpiperazinyl)propyl]acetamideQazCovid-in
go.drugbank.com/drugs/DB16441InvestigationalThe QazCovid-in vaccine, an inactivated vaccine, was developed and tested in the Kazakh Research Institute for Biological Safety Problems[L30628]. … It demonstrated high efficacy, safety, and immunogenicity at 96% in initial Phase I and II trials (NCT04530357), and will now be undergoing upcoming Phase III trials[L30633, L30638].
Telratolimod
go.drugbank.com/drugs/DB19590InvestigationalTelratolimod is under investigation in clinical trial NCT06680479 (Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy … The usage of the INN stem '-tolimod' in the name indicates that Telratolimod is a toll-like receptor (TLR) agonist.
Rezivertinib
go.drugbank.com/drugs/DB21471InvestigationalRezivertinib is under investigation in clinical trial NCT06955325 (Umbrella Trial of Adjuvant Therapy in Completely Resected High-risk Stage IA-IB NSCLC: Focus on Driver Mutations). … The usage of the INN stem '-ertinib' in the name indicates that Rezivertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Tuxobertinib
go.drugbank.com/drugs/DB21508InvestigationalTuxobertinib is under investigation in clinical trial NCT04209465 (A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.). … The usage of the INN stem '-ertinib' in the name indicates that Tuxobertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Palifosfamide
go.drugbank.com/drugs/DB05668InvestigationalIfosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.
Acetylcysteine zidrimer
go.drugbank.com/drugs/DB16496InvestigationalSynonyms: Dendrimer N-acetyl-cysteineAspergillus niger var. niger
go.drugbank.com/drugs/DB10426ApprovedAspergillus niger var. niger extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureAureobasidium pullulans var. pullutans
go.drugbank.com/drugs/DB10427ApprovedAureobasidium pullulans var. pullutans extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture