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ATN-161
go.drugbank.com/drugs/DB05491InvestigationalATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. … expected to extend to a variety of cancers.
Andrographolide
go.drugbank.com/drugs/DB05767InvestigationalAndrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. … The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.
ORG-34517
go.drugbank.com/drugs/DB05423InvestigationalIt has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high.
(S)-Warfarin
go.drugbank.com/drugs/DB14055InvestigationalS-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C18 SubstratesAsundexian
go.drugbank.com/drugs/DB19088InvestigationalAsundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk … Transient Ischemic Attack, a So-called Mini Stroke).
Azimilide
go.drugbank.com/drugs/DB04957InvestigationalAzimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: 1-((5-(P-CHLOROPHENYL)FURFURYLIDENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)HYDANTOINGlucose-6-Phosphate
go.drugbank.com/drugs/DB03581ExperimentalAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. … It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media
go.drugbank.com/drugs/DB15728ExperimentalOne of these companies, Aspire, has created their own product, ACT-20 Conditioned Medium as a product for testing. … In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic.