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Displaying results 5761 - 5770 of 9895 in total
  1. Drug

    ISA101b

    go.drugbank.com/drugs/DB18694
    Investigational

    ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.

  2. Drug

    Metelimumab

    go.drugbank.com/drugs/DB18695
    Experimental

    Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.

  3. Drug

    Irpagratinib

    go.drugbank.com/drugs/DB18732
    Investigational

    Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.

    Synonyms: 2-Propenamide, N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-, N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide
  4. Drug

    Donidalorsen

    go.drugbank.com/drugs/DB18751
    ApprovedInvestigational

    Hereditary angioedema (HAE) is a rare genetic disease characterized by recurrent episodes of severe swelling induced by excessive production of bradykinin. … [A274308] Donidalorsen is a ligand-conjugated antisense oligonucleotide that reduces plasma prekallikrein production, thereby reducing bradykinin production and preventing the initiation of attacks.

    Synonyms: DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RA-SP-G-SP-T-SP-M5C-SP-T-SP-M5C-SP-T-SP-T-SP-G-SP-G-SP-M5C-SP, -(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL)
  5. Drug

    Diaminopyrimidine oxide

    go.drugbank.com/drugs/DB18756
    Approved

    Diaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth.

  6. Drug

    CL-315585

    go.drugbank.com/drugs/DB18758
    Experimental

    CL-315585 is the D isomer of [Verteporfin].

    Synonyms: Bpd-ma(sub d), Verteporfin d isomer
  7. Drug

    Sacituzumab tirumotecan

    go.drugbank.com/drugs/DB18777
    Investigational

    Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

  8. Drug

    Amlitelimab

    go.drugbank.com/drugs/DB18835
    Investigational

    Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years

  9. Drug

    Farletuzumab ecteribulin

    go.drugbank.com/drugs/DB18857
    Investigational

    a Folate Receptor Alpha (Frα)-targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types). … Farletuzumab ecteribulin is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and Efficacy of Morab-202 (Herein Referred to as Farletuzumab Ecteribulin),

  10. Drug

    Fianlimab

    go.drugbank.com/drugs/DB18858
    Investigational

    Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or

    Synonyms: Anti-lag-3 monoclonal antibody regn3767