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Treosulfan
go.drugbank.com/drugs/DB11678ApprovedInvestigationalTreosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation. … [L52245] It was approved by the EMA in June 2019[L16965] and by the FDA in January 2025 for use in combination with [fludarabine].[L52575]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: Treosulfan for InjectionFaricimab
go.drugbank.com/drugs/DB15303ApprovedInvestigational[L40026] It received subsequent approval for the same indications in Canada in May 2022. … [L43085] On April 9, 2026, the FDA approved an updated label that extended faricimab treatment for macular edema following retinal vein occlusion (RVO) beyond six months.[L40026]
Products: VABYSMO 6mg/0.05mL Solution for Intravitreal InjectionMethoxy PEG-12 retinamide
go.drugbank.com/drugs/DB14142InvestigationalProducts: O Hui Wrinkle Science Wrinkle Repair SerumTechnetium Tc-99m tilmanocept
go.drugbank.com/drugs/DB09266ApprovedDTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label]. … Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging.
Products: Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)Tusamitamab ravtansine
go.drugbank.com/drugs/DB17448InvestigationalTusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).
Synonyms: Maytansin-loaded anti-ceacam5 mabLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalhaving generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).
Categories: P-glycoprotein substratesProducts: Ran-levetiracetam, Van-levetiracetamArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalThe enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: Arsenic Trioxide for Injection, Teva-arsenic Trioxide for InjectionBenzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalpotency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. … Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: BENZATROPINE PHEBRA SOLUTION FOR INJECTION 2 MG/2 MLEdaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigationalHowever, the drug manufacturer, Mitsubishi Tanabe Pharma, withdrew the Marketing Authorization Application (MAA) for edaravone from the European market on May 24, 2019, in response to the request made … [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and South Korea in 2015, followed by the FDA approval in May 2017 [L41810] and Health Canada approval in
Products: RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mLTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigational[A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.[A1492] … Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.
Mixtures: Van-telmisartan-hctz, Van-telmisartan-hctzCategories: Antihypertensive Agents Indicated for Hypertension, P-glycoprotein inhibitors