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Socazolimab
go.drugbank.com/drugs/DB18845InvestigationalSocazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).
Synonyms: Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), disulfide with human monoclonal zkab001 .lambda.-chain, dimerDepemokimab
go.drugbank.com/drugs/DB18846ApprovedInvestigational[A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment. … Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug.
Categories: Interleukin-5 AntagonistSynonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimerRosnilimab
go.drugbank.com/drugs/DB18851InvestigationalRosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).
Synonyms: Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa.-chain, dimerNofazinlimab
go.drugbank.com/drugs/DB18852InvestigationalNofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Synonyms: Recombinant pd-1 mab cs1003, Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa.Etigilimab
go.drugbank.com/drugs/DB18854InvestigationalEtigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32Povorcitinib
go.drugbank.com/drugs/DB18855InvestigationalPovorcitinib is under investigation in clinical trial NCT06113445 (A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)).
Gatipotuzumab
go.drugbank.com/drugs/DB18861InvestigationalGatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gexâ„¢ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).
Ginisortamab
go.drugbank.com/drugs/DB18863InvestigationalGinisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced
Synonyms: Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide with human monoclonal ucb6114 .kappa.-chain, dimerVibecotamab
go.drugbank.com/drugs/DB18872InvestigationalVibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Synonyms: Anti-cd123 x anti-cd3 bispecific antibody xmab14045Zigakibart
go.drugbank.com/drugs/DB18892InvestigationalZigakibart is under investigation in clinical trial NCT05852938 (A Study of BION-1301 in Adults With Iga Nephropathy).