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Oxyphenisatin acetate
go.drugbank.com/drugs/DB14627ApprovedWithdrawnThe FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]
Glycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalFDA approved on February 1, 2013.
Brolucizumab
go.drugbank.com/drugs/DB14864ApprovedInvestigational[L9089] Brolucizumab was granted FDA approval in October 2019.[L9089]
Ranibizumab
go.drugbank.com/drugs/DB01270ApprovedInvestigational[L41399] In August 2022, other biosimilars CIMERLI, RAIVISIO, and RANOPTO were approved by the FDA, EC, and Health Canada respectively.[L42625,L43513,L49141] … [A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission (EC) in 2007.[L41429] It is marketed under the brand names LUCENTIS and SUSVIMO.
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS...
Palifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalPalifermin was granted FDA approval on 15 December 2004.[L17933]
Sonidegib
go.drugbank.com/drugs/DB09143ApprovedInvestigationalIt was FDA approved in 2015 for the treatment of basal cell carcinoma.
Cinnamaldehyde
go.drugbank.com/drugs/DB14184ApprovedCinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to...
Ammonia
go.drugbank.com/drugs/DB11118ApprovedInvestigationalAmmonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a...