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Oxyphenisatin acetate
go.drugbank.com/drugs/DB14627ApprovedWithdrawnThe FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]
Glycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalFDA approved on February 1, 2013.
Brolucizumab
go.drugbank.com/drugs/DB14864ApprovedInvestigational[L9089] Brolucizumab was granted FDA approval in October 2019.[L9089]
Mecasermin rinfabate
go.drugbank.com/drugs/DB14751ApprovedInvestigationalMecasermin rinfabate manufactured by Insmed Incorporated under the brand name Iplex was approved by the FDA in 2005[L5722].
Pralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigational[A202049, A202055, L15986] Although a phase 1/2 trial of pralsetinib termed ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, 2020, for the treatment
Ranibizumab
go.drugbank.com/drugs/DB01270ApprovedInvestigational[L41399] In August 2022, other biosimilars CIMERLI, RAIVISIO, and RANOPTO were approved by the FDA, EC, and Health Canada respectively.[L42625,L43513,L49141] … [A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission (EC) in 2007.[L41429] It is marketed under the brand names LUCENTIS and SUSVIMO.
Palifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalPalifermin was granted FDA approval on 15 December 2004.[L17933]
Sonidegib
go.drugbank.com/drugs/DB09143ApprovedInvestigationalIt was FDA approved in 2015 for the treatment of basal cell carcinoma.
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS...