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Displaying results 5891 - 5900 of 10000 in total
  1. Drug

    Allopurinol riboside

    go.drugbank.com/drugs/DB17738
    Experimental

    Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at the 1-position.

  2. Drug

    Higenamine

    go.drugbank.com/drugs/DB12779
    Investigational

    Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Devafidugene civaparvovec

    go.drugbank.com/drugs/DB16790
    Investigational

    Devafidugene civaparvovec is an investigational _in vivo_ genome editing product. … It uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme.

  4. Drug

    CY-1503

    go.drugbank.com/drugs/DB17605
    Investigational

    It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions.

  5. Drug

    NGN-401

    go.drugbank.com/drugs/DB18594
    Investigational

    Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome. … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding

    Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2
  6. Drug

    WNY0824

    go.drugbank.com/drugs/DB23606
    Experimental

    [A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258]

    Synonyms: PLK1/BRD4-IN-1
  7. Drug

    BHV-1300

    go.drugbank.com/drugs/DB22673
    Investigational

    BHV-1300 is a IgG1,2,4 selective degrader being investigated for the treatment of Grave's disease.

  8. Drug

    CoVac-1

    go.drugbank.com/drugs/DB16429
    Investigational

    It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults (pVAC))[L30428] and aims to induce broad … Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588].

  9. Drug

    Streptococcus pneumoniae type 9N capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB19342
    ApprovedInvestigational

    _ serotype 9N individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of _Corynebacterium diphtheriae_ strain C7 (β197). … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

    Synonyms: Streptococcus pneumoniae type 9N capsular polysaccharide diphtheria CRM197 protein conjugate antigen
  10. Drug

    Obinepitide

    go.drugbank.com/drugs/DB05045
    Experimental

    These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. … In obinepitide, the properties of both of these hormones have been implanted into a single molecule.