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2,3-Di-O-Sulfo-Alpha-D-Glucopyranose
go.drugbank.com/drugs/DB02879ExperimentalSynonyms: 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose(3s)-3,4-Di-N-Hexanoyloxybutyl-1-Phosphocholine
go.drugbank.com/drugs/DB03827ExperimentalSynonyms: (3s)-3,4-Di-N-Hexanoyloxybutyl-1-Phosphocholine1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
go.drugbank.com/drugs/DB02170ExperimentalSynonyms: 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-OneZenocutuzumab
go.drugbank.com/drugs/DB15559ApprovedInvestigationalZenocutuzumab is a low-fucose humanized full-length immunoglobulin G1 (IgG1) bispecific HER2- and HER3-directed bispecific antibody. … [L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher.
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and her3 receptors.), Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimerTalquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalIt consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. … [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL1,2-Di-N-Pentanoyl-Sn-Glycero-3-Dithiophosphocholine
go.drugbank.com/drugs/DB02225ExperimentalSynonyms: 1,2-Di-N-Pentanoyl-Sn-Glycero-3-DithiophosphocholineApadamtase alfa
go.drugbank.com/drugs/DB15164ApprovedInvestigationalThrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 is responsible for the microangiopathic complications associated with cTTP
Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifsObecabtagene autoleucel
go.drugbank.com/drugs/DB17362ApprovedInvestigational[L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein
go.drugbank.com/drugs/DB33819ExperimentalSynonyms: Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoproteinVeverimer
go.drugbank.com/drugs/DB18977InvestigationalVeverimer is under investigation in clinical trial NCT03390842 (Long-term Safety Extension to Study TRCA-301).
Synonyms: 1,3-propanediamine, n1,n3-di-2-propen-1-yl-, polymer with 1,2-dichloroethane and 2-propen-1-amine, N1,n3-bis(prop-2-en-1-yl)propan-1,3-diamine copolymer with 1,2-dichloroethane and prop-2-en-1-amine