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Displaying results 51 - 60 of 144472 in total
  1. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  2. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    Median survival is encouraging and correlates strongly with dose levels.[A260416] … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic block copolymers.

    Synonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127
  3. Drug

    VA-MENGOC-BC®

    go.drugbank.com/drugs/DB15800
    Experimental

    VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. … The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C.

    Synonyms: Meningococcal polysaccharide vaccine groups B and C
  4. Drug

    PlasmaCord

    go.drugbank.com/drugs/DB16363
    Experimental

    PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. … [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).

    Synonyms: Human umbilical cord and placental blood plasma
  5. Drug

    Taraxacum officinale leaf

    go.drugbank.com/drugs/DB14342
    Investigational

    Taraxacum officinale leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Blowball Leaf, Dandelion Leaf
  6. Drug

    renizgamglogene autogedtemcel

    go.drugbank.com/drugs/DB25530
    Investigational

    renizgamglogene autogedtemcel is a biologic drug. renizgamglogene autogedtemcel is under investigation in clinical trial NCT05444894 (EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Depe...

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 promoters, autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP) at the HBG1 and HBG2 promoters
  7. Drug

    AFM-13

    go.drugbank.com/drugs/DB17404
    Investigational

    Synonyms: Recombinant antibody construct against human CD30 and CD16A
  8. Drug

    Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles

    go.drugbank.com/drugs/DB33825
    Experimental

    Synonyms: Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles
  9. Drug

    DF-1001

    go.drugbank.com/drugs/DB18231
    Investigational

    Synonyms: Heterodimeric multi-specific IgG1 antibody targeting human epidermal growth factor receptor 2 (HER2) and NKG2D on natural killer (NK) and cytotoxic T-cells
  10. Drug

    Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

    go.drugbank.com/drugs/DB10990
    Approved

    These are heat inactivated and purified. … Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received

    Synonyms: Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T)