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Risankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigational[L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.
Products: SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/ML, SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/MLAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole. … [L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms.
Products: ABAXON AP 1MG, TAFIL 1.0MG TABLLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigational[L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment of Trk-positive solid tumors. … It was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805]
Products: VITRAKVI ORAL SOLUTION 20MG/ML, VITRAKVI®CÁPSULAS DE 100MGAfoxolaner
go.drugbank.com/drugs/DB11369ExperimentalVet approvedMixtures: Nexgard Spectra 150mg/30mg Chewable Tablets for Dogs >30-60kg, Nexgard Spectra 75mg/15mg Chewable Tablets for Dogs >15-30kgProducts: NexGard 28mg chewable tablets for dog > 4-10kg, NexGard 11mg chewable tablets for dogs 2-4kgDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigationalIn its statement, the FDA has mentioned that increased risk of venous thromboembolism with oral contraceptives such as drospirenone exists but remains lower than the risk of this condition during pregnancy … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy.
Mixtures: MESAMES 3MG/0.03MG, Cleonita 3mg/0.02mg TabletsProducts: SLINDA FILM-COATED TABLETS 4MGTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigational[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Products: PALEXIS® RETARD 50MG, NUCYNTA ER Tablets 50mgNilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Products: Anandron Tab 50mg, Anandron Tab 100mgMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedMeloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis.
Products: MEXIMED®15MG, MELOXICAM 15MGAsunaprevir
go.drugbank.com/drugs/DB11586ApprovedWithdrawn[A32528] It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on April 22, 2016. The commercialization of asunaprevir was cancelled one year later on October 16, 2017.[L1113]
Products: SUNVEPRA CAPSULE 100MG, SUNVEPRA® 100MG CÁPSULAS BLANDASVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigationalIts active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. … [L43030] The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in 1993 and the extended-release formulation, Effexor XR, was later introduced in 1997.
Products: VENXOR 50MG TABLET, Effexor Tablets, 50mg