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SR 121463
go.drugbank.com/drugs/DB05455InvestigationalIt is a candidate for control of hyponatremia and in the treatment of syndrome of inappropriate secretion of anti-diuretic hormone (SIADH). … SR 121463 is a nonpeptide aquaretic compound with potent selective antagonism of the vasopressin V2 (V1b) receptor subtype.
ISIS 325568
go.drugbank.com/drugs/DB06099InvestigationalISIS 325568 is a generation 2.2 antisense drug that targets the glucagon receptor (GCGR). … It was under investigation in clinical trial NCT00519727 (Safety Study of ISIS 325568 in Healthy Volunteers) for lowering blood glucose and helping control type 2 diabetes.
Uprifosbuvir
go.drugbank.com/drugs/DB15206Investigationalunder investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT
Cefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedCefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. … The advantage of using injectable antibiotics is not missing a dose that can allow partially resistant microbes to recover during missed doses.
Inbakicept
go.drugbank.com/drugs/DB16479InvestigationalIt is one of the active ingredients in Anktiva, a combination product also containing [nogapendekin alfa], where a single inbakicept is complexed with two nogapendekin alfa components. … Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein.
Synonyms: ALT-803 COMPONENT IL-15R.ALPHA.SU/FC FUSION PROTEINErtiprotafib
go.drugbank.com/drugs/DB06521ExperimentalIn insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test. … Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes.
Inhibitor of P38 Kinase
go.drugbank.com/drugs/DB01953ExperimentalInhibitor of P38 Kinase is a solid. This compound belongs to the indoles. These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole.
5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole
go.drugbank.com/drugs/DB08724ExperimentalThese are aromatic compounds containing an ether group substituted with a benzene ring. This medication is known to target genome polyprotein. … 5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers.
Fluciclatide
go.drugbank.com/drugs/DB14842InvestigationalFluciclatide, an investigational radiotracer intended for PET imaging, was under investigation in clinical trials NCT00565721 and NCT01961583 to evaluate its ability to detect tumors and angiogenesis.
Probiorinse
go.drugbank.com/drugs/DB15870ExperimentalProbiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.