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Foslevodopa
go.drugbank.com/drugs/DB16683ApprovedFoslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants
Synonyms: 3-hydroxy-O-phosphono-L-tyrosine, Levodopa-4'-monophosphateBMS-986104
go.drugbank.com/drugs/DB15214InvestigationalBMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
MKC1106-PP
go.drugbank.com/drugs/DB06030ExperimentalThe plasmid portion is a recombinant plasmid expressing segments of the 2 target antigens, PRAME and PSMA. … MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM.
Chikungunya virus Senegal strain 37997 envelope protein E1
go.drugbank.com/drugs/DB21767ApprovedInvestigationalOne of three components of a recombinant Chikungunya virus vaccine called Vimkunya.
Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalIt has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy. … Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels
Categories: Heterocyclic Compounds, 1-RingNB-001
go.drugbank.com/drugs/DB12716InvestigationalNB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
Categories: Heterocyclic Compounds, 2-RingErtumaxomab
go.drugbank.com/drugs/DB18923InvestigationalErtumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy).
Synonyms: Anti-cd3 x anti-her-2-neu bispecific monoclonal antibodyDA-8031
go.drugbank.com/drugs/DB19024InvestigationalDA-8031 is under investigation in clinical trial NCT01798667 (Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 1-(3-(DIMETHYLAMINO)PROPYL)-1,3-DIHYDRO-1-(4-METHOXYPHENYL)-5-ISOBENZOFURANCARBONITRILE, 5-ISOBENZOFURANCARBONITRILE, 1-(3-(DIMETHYLAMINO)PROPYL)-1,3-DIHYDRO-1-(4-METHOXYPHENYL)-Nacubactam
go.drugbank.com/drugs/DB15353InvestigationalNacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).
Categories: Heterocyclic Compounds, 1-RingQR-334
go.drugbank.com/drugs/DB05473ExperimentalQR-334 is under investigation for the treatment of sialorrhea. Sialorrhea is an excess secretion of saliva produced by the salivary glands, resulting in drooling. … The symptom is associated with many diseases including Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, Cerebral Palsy, Parkinson's Disease, and Muscular Dystrophy.