Search

2,5-di-tert-butylhydroquinone

Theralizumab

After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]

Mimopezil

Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease.

Omburtamab

[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. … [A191829] Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/leptomeningeal Metastases).

Carbomer homopolymer type C

Carbomer homopolymer type C is a high molecular polyanionic substance tested for antiulcerogenic activity.

Potassium triiodide

Ioglunide

Ioglunide is a small molecule drug. Ioglunide has a monoisotopic molecular weight of 806.86 Da.

Icotinib

Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc

Lixmabegagene relduparvovec

It is under development for the treatment of GM1 gangliosidosis.[L45929]

ALT-2074

An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. … BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase.