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NasoVAX
go.drugbank.com/drugs/DB15859InvestigationalThe compound has already shown to be tolerated with no adverse effects or fever in healthy individuals with a nearly 6-fold cellular immune response in comparison to an injectable vaccine[L16313]. … It is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells[L16313].
Cretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalIt has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy. … CG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid.
UDP-alpha-D-glucuronic acid
go.drugbank.com/drugs/DB03041ExperimentalIt may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. … A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis.
Categories: Heterocyclic Compounds, 1-RingSynonyms: UDP-D-glucuronate, UDP-alpha-D-glucuronateMaridebart Cafraglutide
go.drugbank.com/drugs/DB19339InvestigationalMaridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity … , With or Without Type 2 Diabetes Mellitus).
Synonyms: thioether) with 7-37-glucagon-like peptide I [8-(, gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-33*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K1203-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide
go.drugbank.com/drugs/DB08092Experimental3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide is a solid. This compound belongs to the phenylmorpholines. … These are aromatic compounds containing a morpholine ring and a benzene ring linked to each other through a CC or a CN bond. This drug targets mitogen-activated protein kinase 14.
Synonyms: 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide4-Phenylfentanyl
go.drugbank.com/drugs/DB09168ExperimentalIllicitthiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil. … 4-Phenylfentanyl is a sythetic opioid derived from fentanyl. 4-Phenylfentanyl is around 8x the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted
Synonyms: N-(1-Phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide, 4-PhenylfentanylBlack widow spider antivenin (equine)
go.drugbank.com/drugs/DB14113ApprovedBlack widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]
Synonyms: LATRODECTUS IMMUNE F(AB)2Risuteganib
go.drugbank.com/drugs/DB14911InvestigationalRisuteganib is under investigation in clinical trial NCT02348918 (Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macular Edema).
Ispectamab debotansine
go.drugbank.com/drugs/DB18456InvestigationalIspectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid
Fazpilodemab
go.drugbank.com/drugs/DB18924InvestigationalFazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis
Synonyms: Bfkb-8488a (bispecific antibody designed to mimic the metabolic hormone fgf21)., anti-KLB (1-450) [VH (Homo sapiens IGHV3-66*01 (