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Elezanumab
go.drugbank.com/drugs/DB15240InvestigationalElezanumab is under investigation in clinical trial NCT03737812 (A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis).
Iscalimab
go.drugbank.com/drugs/DB15260InvestigationalIscalimab is under investigation in clinical trial NCT03905525 (Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome).
Poziotinib
go.drugbank.com/drugs/DB12114InvestigationalPoziotinib has been used in trials studying the treatment of Breast Cancer, Metastatic Breast Cancer, Increased Drug Resistance, Adenocarcinoma of Lung Stage IV, and Adenocarcinoma of Lung Stage IIIB,
Quinolinic Acid
go.drugbank.com/drugs/DB01796ExperimentalElevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem] … A metabolite of tryptophan with a possible role in neurodegenerative disorders.
ASP-4058
go.drugbank.com/drugs/DB11819InvestigationalASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.
Tozorakimab
go.drugbank.com/drugs/DB16473Investigationalexacerbations), and NCT06040086 (recruiting; symptomatic COPD with a history of exacerbations). … completed with results; diabetic kidney disease), NCT05624450 (recruiting; viral lung infection requiring supplemental oxygen), NCT05742802 (recruiting; long-term study in COPD patients with a history of
Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalIt has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
CP-39,332
go.drugbank.com/drugs/DB09193ExperimentalHowever, none of the members of this stereoisomers has been marketed. … It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency.
Deanol
go.drugbank.com/drugs/DB13352InvestigationalDeanol has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia. … Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups.
OPC-28326
go.drugbank.com/drugs/DB05461ExperimentalIt is currently being investigated in the treatment of peripheral vascular diseases and Raynaud's syndrome. … At low doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2-adrenoceptors while having minimal action on systemic blood pressure, heart rate and coronary