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CAR BCMA-CS1
go.drugbank.com/drugs/DB17313ExperimentalCAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Synonyms: BCMA-CS1 cCAR T cell therapyGemogenovatucel-T
go.drugbank.com/drugs/DB17412Investigational[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Synonyms: Gemogenovatucel-TErfonrilimab
go.drugbank.com/drugs/DB17446InvestigationalErfonrilimab is a bispecific monoclonal antibody directed against both the programmed cell death-1 ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA4).
UCART22
go.drugbank.com/drugs/DB17466InvestigationalUCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.
Synonyms: Allogeneic gene-edited CAR T cells UCART22, Allogeneic TALEN gene-edited CAR T-Cells UCART22M-701
go.drugbank.com/drugs/DB17504ExperimentalM-701 is a recombinant anti-EpCAM/CD3 bispecific antibody.
RO7296682
go.drugbank.com/drugs/DB17531InvestigationalRO7296682 is a monoclonal antibody against CD25 (IL-2R alpha) expressed on tumour-infiltrating regulatory T (T<sub>reg</sub>) cells.
Transfluthrin
go.drugbank.com/drugs/DB15117InvestigationalTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
Vocimagene amiretrorepvec
go.drugbank.com/drugs/DB15331InvestigationalVocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
Cerdulatinib
go.drugbank.com/drugs/DB15499InvestigationalCerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Tolboxane
go.drugbank.com/drugs/DB19778ExperimentalThe usage of the INN stem '-oxan(e)' in the name indicates that Tolboxane is a benzodioxane derivative. Tolboxane has a monoisotopic molecular weight of 232.16 Da.