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TOP-1288
go.drugbank.com/drugs/DB14839InvestigationalTOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis
AP5346
go.drugbank.com/drugs/DB04992InvestigationalAP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. … It is being pursued by Access Pharmaceuticals, Inc.
Amaranthus spinosus pollen
go.drugbank.com/drugs/DB10484ApprovedAmaranthus spinosus pollen is the pollen of the Amaranthus spinosus plant. Amaranthus spinosus pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractAmbrosia bidentata pollen
go.drugbank.com/drugs/DB10491ApprovedAmbrosia bidentata pollen is the pollen of the Ambrosia bidentata plant. Ambrosia bidentata pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractAmbrosia chamissonis pollen
go.drugbank.com/drugs/DB10948ApprovedAmbrosia chamissonis pollen is the pollen of the Ambrosia chamissonis plant. Ambrosia chamissonis pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractEpiVacCorona
go.drugbank.com/drugs/DB16439InvestigationalIt is currently being tested in Phase I/II clinical trials for safety and immunogenicity (NCT04527575)[L30608, L30613]. … EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus[L30608].
SPP1148
go.drugbank.com/drugs/DB05203ExperimentalSPP1148, the most promising compound from a new series of renin inhibitors for the treatment of hypertension and related end-organ disease.
Zilovertamab vedotin
go.drugbank.com/drugs/DB18457InvestigationalZilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (
Cytochrome P450 1A1
go.drugbank.com/bio_entities/BE0009369EnzymeRatMay play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues. … Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation (By similarity). Catalyzes the epoxidation of double bonds of certain PUFA (PubMed:20972997).
Synonyms: Cytochrome P450 form 6Bezitramide
go.drugbank.com/drugs/DB01459ApprovedIllicitWithdrawnAfter cases of fatal overdose in the Netherlands in 2004 the drug was withdrawn from the market. Bezitramide has never been FDA approved and is currently a schedule II drug. … Bezitramide is a narcotic analgesic which was discovered in 1961, clinically tested around the 1970's [A14383], and marketed under the name Burgodin.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome