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Diethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedIt is widely used to repel biting pests such as mosquitoes and ticks. … And, despite concerns over excessive exposure to the chemical, appropriate usage of the chemical at the recommended dosages and routes of administration have generally proven to be safe - even when most
Categories: Compounds used in a research, industrial, or household settingMethyl salicylate
go.drugbank.com/drugs/DB09543ApprovedInvestigationalVet approvedIt is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions. … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments.
Mixtures: Pommade Au The Des Bois, Cho-A Point PlasterCategories: Compounds used in a research, industrial, or household settingDefibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalIt is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. In the USA it is was approved in March, 2016 as Defitelio. … Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA.
Ociperlimab
go.drugbank.com/drugs/DB18947InvestigationalOciperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage
Synonyms: Immunoglobulin g1, anti-(human receptor tigit) (human-mus musculus monoclonal bgb-a1217 .gamma.1-chain), disulfide with human-mus musculus monoclonal bgb-a1217 .kappa.-chain, dimerTumour necrosis factor receptor-associated periodic syndrome
go.drugbank.com/conditions/DBCOND0008484Drugs: CanakinumabSynonyms: TNF-receptor Associated Periodic Syndromes (TRAPS), TNF receptor-associated periodic fever syndromeCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Products: CEFUROXIM AL 250, CEFUROXIM AL 500Palonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalAs of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Categories: Serotonin Receptor Antagonists, Serotonin 3 Receptor AntagonistsDihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalRecent improvements have been made in the design of intranasal delivery devices allowing for greater delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity. … A 9,10alpha-dihydro derivative of [ergotamine]. Dihydroergotamine is used as an abortive therapy for migraines.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Serotonin Receptor AgonistsTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Qvaya 1 mg/ml Emulsion zur Anwendung auf der HautMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigational[A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper … Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries.
Categories: Compounds used in a research, industrial, or household setting