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AZD-6482
go.drugbank.com/drugs/DB14980InvestigationalAZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
Vitex agnus-castus fruit extract
go.drugbank.com/drugs/DB13193InvestigationalClinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast pain (mastalgia). … Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus.
GB-13
go.drugbank.com/drugs/DB18387ExperimentalGB-13 is a genetically engineered recombinant protein consisting of an IL13Ra2-targeted genetically engineered mutant of IL-13 and PE4E, a derivative of Pseudomonas exotoxin A.
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
N,N,N-trimethylglycinium
go.drugbank.com/drugs/DB04455InvestigationalAs a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. … A naturally occurring compound that has been of interest for its role in osmoregulation.
APR-548
go.drugbank.com/drugs/DB17546InvestigationalAPR-548 is an analog of [eprenetapopt] and a reactivator of mutant p53.
Stibophen
go.drugbank.com/drugs/DB13236ExperimentalStibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
H-151
go.drugbank.com/drugs/DB29149ExperimentalH-151 is an inhibitor of the stimulator of interferon genes (STING) protein.
Gevokizumab
go.drugbank.com/drugs/DB12119InvestigationalGevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.
ISIS 325568
go.drugbank.com/drugs/DB06099InvestigationalIt was under investigation in clinical trial NCT00519727 (Safety Study of ISIS 325568 in Healthy Volunteers) for lowering blood glucose and helping control type 2 diabetes.