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Amfecloral
go.drugbank.com/drugs/DB08924ExperimentalFor a short period of time, it was available under the brand Acutran and indicated as an appetite suppressant, but this product no longer exists. … It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active
Formoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration … of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication.
Ziprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigationalgenerally thought to be as efficacious as first generation antipsychotics but differ in their adverse effect profiles. … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior.
Products: ZIPRASIDONE MYLAN GENERICSTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalAs recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate.
Progesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedProgesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. … Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label].
Metformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207]
Products: METFORMINA DOC GENERICI, METFORMINA DOC GENERICSGlycyrrhizic acid
go.drugbank.com/drugs/DB13751ApprovedInvestigational[A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener. … [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis.
Repotrectinib
go.drugbank.com/drugs/DB16826ApprovedInvestigational[A262066] On November 15th, 2023, the FDA approved repotrectinib under the brand name Augtyro for the treatment of locally advanced or metastatic ROS1-Positive NSCLC.
Terlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigational[L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions with diminished vasomotor tone. … Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin.
Hexylresorcinol
go.drugbank.com/drugs/DB11254ApprovedThe compound may also be used commonly in various commercial cosmetic anti-aging creams while ongoing studies research the possibility of using hexylresorcinol as an anti-cancer therapy - indications all