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Viralym-C
go.drugbank.com/drugs/DB17975InvestigationalViralym-C is an investigational T-cell immunotherapy developed by ViraCyte. It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. … It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]
Atrazine
go.drugbank.com/drugs/DB07392ExperimentalAtrazine is a selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans. … Acutely poisoned sheep and cattle may show muscular spasms, fasciculations, stiff gait, increased respiratory rates, adrenal degeneration, and congestion of the lungs, liver, and kidneys.
Categories: Compounds used in a research, industrial, or household settingAdlinacogene civaparvovec
go.drugbank.com/drugs/DB16788InvestigationalAdlinacogene civaparvovec is an investigational _in vivo_ genome editing therapeutic product. … [L46711] Developed by Sangamo Therapeutics Inc., it is being investigated for the treatment of hemophilia B.[L46706]
Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia. … CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions.
Piperidione
go.drugbank.com/drugs/DB13224ExperimentalPiperidione was cough medicine marketed by Roche under the trade name Sedulon.
Categories: Cough and Cold PreparationsEmodepside
go.drugbank.com/drugs/DB11403InvestigationalVet approvedEmodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively
Categories: Amino Acids, Peptides, and ProteinsPhosphonotyrosine
go.drugbank.com/drugs/DB01962ExperimentalAn amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
Amilomotide
go.drugbank.com/drugs/DB05150InvestigationalCAD106 is an immunotherapeutic product in development for the treatment of Alzheimer's disease. … It is designed to induce antibodies against the beta-amyloid-protein that inhibit the formation of plaques in the brain of Alzheimer's disease patients.
CHGN111
go.drugbank.com/drugs/DB06376ExperimentalCHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase. … Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative
AVR-RD-01
go.drugbank.com/drugs/DB17651InvestigationalAVR-RD-01 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-01 is being investigated for Fabry Disease.[L45963, L45968]