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Displaying results 6501 - 6510 of 10000 in total
  1. Drug

    Dasantafil

    go.drugbank.com/drugs/DB19918
    Experimental

    The usage of the INN stem '-afil' in the name indicates that Dasantafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. Dasantafil has a monoisotopic molecular weight of 521.13 Da.

  2. Drug

    Nifurizone

    go.drugbank.com/drugs/DB19694
    Experimental

    The usage of the INN stem 'nifur-' in the name indicates that Nifurizone is a 5-nitrofuran derivative. Nifurizone has a monoisotopic molecular weight of 307.09 Da. … The usage of the INN stem '-zone' in the name indicates that Nifurizone is a anti-inflammatory analgesic, phenylbutazone derivative.

  3. Drug

    Phosphoaminophosphonic Acid-Adenylate Ester

    go.drugbank.com/drugs/DB04395
    Experimental

    It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem] … An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom.

  4. Drug

    Nifurethazone

    go.drugbank.com/drugs/DB20112
    Experimental

    The usage of the INN stem 'nifur-' in the name indicates that Nifurethazone is a 5-nitrofuran derivative. Nifurethazone has a monoisotopic molecular weight of 269.11 Da. … The usage of the INN stem '-azone' in the name indicates that Nifurethazone is a anti-inflammatory analgesic, phenylbutazone derivative.

  5. Drug

    Gamcemetinib

    go.drugbank.com/drugs/DB21624
    Investigational

    Gamcemetinib has a monoisotopic molecular weight of 469.1 Da. … The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor.

  6. Drug

    HTPEP-001

    go.drugbank.com/drugs/DB18730
    Experimental

    HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-β). It is being investigated for the treatment of fibrosis.[A263527]

  7. Drug

    TRO40303

    go.drugbank.com/drugs/DB16031
    Investigational

    TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute

  8. Drug

    AIM-102

    go.drugbank.com/drugs/DB16176
    Investigational

    AIM-102 is under investigation in clinical trial NCT01501942 (Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic

  9. Drug

    Brivanib

    go.drugbank.com/drugs/DB11958
    Investigational

    Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. … Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).

  10. Drug

    Indusatumab vedotin

    go.drugbank.com/drugs/DB12413
    Investigational

    Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and