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Recombinant Super-Compound Interferon
go.drugbank.com/drugs/DB15752InvestigationalRecombinant super-compound interferon (rSIFN-co) is a recombinant version of interferon alpha with modified spatial configuration. This interferon has antiviral and antitumor activity.
Synonyms: rSIFN-coMepiprazole
go.drugbank.com/drugs/DB09197ExperimentalIt acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake and induce the release of serotonin, dopamine, and norepinephrine to varying extents.
Homocysteine
go.drugbank.com/drugs/DB04422InvestigationalHomocysteine is a thiol-containing amino acid formed by a demethylation of methionine.
TTAX01
go.drugbank.com/drugs/DB17928InvestigationalTTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.[L47246]
SynOV1.1
go.drugbank.com/drugs/DB17539InvestigationalSynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech. … It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF).
VPM4001
go.drugbank.com/drugs/DB05089ExperimentalIt consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ). … Interferon-γ enhances presentation of tumour antigens, whereas interleukin-2 stimulates T cells.
Cyamemazine
go.drugbank.com/drugs/DB09000ExperimentalCyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
ATG-101
go.drugbank.com/drugs/DB17162InvestigationalATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors
RO7296682
go.drugbank.com/drugs/DB17531InvestigationalRO7296682 is under investigation in clinical trial NCT04642365 (A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors. … RO7296682 is a monoclonal antibody against CD25 (IL-2R alpha) expressed on tumour-infiltrating regulatory T (T<sub>reg</sub>) cells.
Synonyms: RO 7296682, RO-7296682Lemzoparlimab
go.drugbank.com/drugs/DB17572InvestigationalLemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or