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ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
Rocapuldencel-T
go.drugbank.com/drugs/DB17588InvestigationalRocapuldencel-T is an autologous dendritic cell immunotherapy that was investigated in NCT02662634 (A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer
Synonyms: Rocapuldencel-TNTLA-2002
go.drugbank.com/drugs/DB17597InvestigationalNTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9.
Emprumapimod
go.drugbank.com/drugs/DB17603InvestigationalEmprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.
Intermedine
go.drugbank.com/drugs/DB17612InvestigationalSynonyms: Ac-ser-tyr-ser-met-glu-his-phe-arg-trp-gly-lys-pro-val-nh2, Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-, l-Categories: Heterocyclic Compounds, 2-RingPXL-770 free acid anhydrous
go.drugbank.com/drugs/DB17615ExperimentalSynonyms: 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo- 5-phenyl-6,7-dihydrothieno(2, 3-b)pyridin-4-olateCategories: Heterocyclic Compounds, 1-RingMubodina
go.drugbank.com/drugs/DB17616ExperimentalIt is a recombinant human minibody directed against complement component C5.
Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1Sinbaglustat
go.drugbank.com/drugs/DB17619ExperimentalSynonyms: (2s,3r,4r,5s)-2-(hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol, (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-Pentylpiperidine-3,4,5-TriolCategories: Heterocyclic Compounds, 1-RingCyclocreatine
go.drugbank.com/drugs/DB17624ExperimentalSynonyms: 1-carboxymethyl-2-imino-imidazolidine, 2-imino-1-imidazolidineacetic acidCategories: Heterocyclic Compounds, 1-RingINZ-701
go.drugbank.com/drugs/DB17629InvestigationalINZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Synonyms: Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 (INZ-701)