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Displaying results 6671 - 6680 of 10000 in total
  1. Drug

    Povafonidine

    go.drugbank.com/drugs/DB21470
    Experimental

    The usage of the INN stem '-nidine' in the name indicates that Povafonidine is a a2 adrenoreceptor agonist. Povafonidine has a monoisotopic molecular weight of 215.12 Da.

  2. Drug

    Xininurad

    go.drugbank.com/drugs/DB21564
    Experimental

    The usage of the INN stem '-inurad' in the name indicates that Xininurad is a urate transporter inhibitor. Xininurad has a monoisotopic molecular weight of 440.91 Da.

  3. Drug

    Ansornitinib

    go.drugbank.com/drugs/DB21577
    Experimental

    The usage of the INN stem '-tinib' in the name indicates that Ansornitinib is a tyrosine kinase inhibitor. Ansornitinib has a monoisotopic molecular weight of 540.25 Da.

  4. Drug

    Gumelutamide

    go.drugbank.com/drugs/DB21615
    Experimental

    The usage of the INN stem '-lutamide' in the name indicates that Gumelutamide is a non-steroid antiandrogen. Gumelutamide has a monoisotopic molecular weight of 420.15 Da.

  5. Drug

    Frevecitinib

    go.drugbank.com/drugs/DB21681
    Investigational

    The usage of the INN stem '-citinib' in the name indicates that Frevecitinib is a Janus kinase inhibitor. Frevecitinib has a monoisotopic molecular weight of 415.18 Da.

  6. Drug

    Odentegravir

    go.drugbank.com/drugs/DB21708
    Experimental

    The usage of the INN stem '-tegravir' in the name indicates that Odentegravir is a HIV integrase inhibitor. Odentegravir has a monoisotopic molecular weight of 421.12 Da.

  7. Drug

    2-Hydroxylpropyl-beta-cyclodextrin

    go.drugbank.com/drugs/DB15146
    Investigational

    Adrabetadex is under investigation in clinical trial NCT03887533 (Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1).

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    SYNB1020

    go.drugbank.com/drugs/DB17667
    Investigational

    It was initially designed to convert ammonia to L-arginine [A258838] and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 2016;[L45988] however, the manufacturer … SYNB1020 is an engineered strain of _Escherichia coli_ Nissle 1917 developed by Synlogic Inc.

  9. Drug

    BW-A 58C

    go.drugbank.com/drugs/DB06740
    Experimental

    BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy … metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.

  10. Drug

    Ofirnoflast

    go.drugbank.com/drugs/DB21679
    Investigational

    Ofirnoflast is under investigation in clinical trial NCT07052006 (HT-6184 in Subjects With MDS). Ofirnoflast has a monoisotopic molecular weight of 501.15 Da. … The usage of the INN stem '-noflast' in the name indicates that Ofirnoflast is a inflammasome protein NLRP3 inhibitor.