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Displaying results 6731 - 6740 of 10000 in total
  1. Drug

    Potrasertib

    go.drugbank.com/drugs/DB21682
    Experimental

    Potrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Potrasertib is a serine/threonine kinase inhibitor. … Potrasertib has a monoisotopic molecular weight of 564.19 Da.

  2. Drug

    Tigemocoxib

    go.drugbank.com/drugs/DB21699
    Experimental

    Tigemocoxib is a small molecule drug. The usage of the INN stem '-coxib' in the name indicates that Tigemocoxib is a selective cyclo-oxygenase inhibitor. … Tigemocoxib has a monoisotopic molecular weight of 334.06 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Deanol

    go.drugbank.com/drugs/DB13352
    Investigational

    Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. … Deanol has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.

    Synonyms: 2-(dimethylamino)ethanol
  4. Drug

    Vercirnon

    go.drugbank.com/drugs/DB15250
    Investigational

    Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. … It is under investigation in clinical trial NCT01611805 (Japanese Phase I of GSK1605786).

  5. Drug

    Gabexate

    go.drugbank.com/drugs/DB12831
    Investigational

    Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. It also known to decrease production of inflammatory cytokines.

  6. Drug

    C326

    go.drugbank.com/drugs/DB06017
    Experimental

    The drug is composed of an IL-6–binding trimer and a IgG-binding domain. … C326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment

  7. Drug

    Tridolgosir

    go.drugbank.com/drugs/DB02034
    Experimental

    An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.

    Synonyms: (1S,2R,8R,8AR)-octahydro-1,2,8-indolizinetriol
  8. Drug

    Golvatinib

    go.drugbank.com/drugs/DB11977
    Investigational

    Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.

    Categories: Heterocyclic Compounds, 1-Ring, Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitors
  9. Drug

    Glembatumumab vedotin

    go.drugbank.com/drugs/DB05996
    Investigational

    A conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.

  10. Drug

    Danegaptide

    go.drugbank.com/drugs/DB11821
    Investigational

    Danegaptide has been investigated for the treatment of Focus of Study is STEMI.