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LYB017
go.drugbank.com/drugs/DB33994ExperimentalLYB017 is a biologic drug. LYB017 is under investigation in clinical trial NCT07831226 (Safety and Immunogenicity of the Recombinant Malaria Vaccines in Healthy Adults Aged 18-59 Years).
ALN-6457
go.drugbank.com/drugs/DB33986ExperimentalALN-6457 is a biologic drug. ALN-6457 is under investigation in clinical trial NCT07832370 (A Trial of ALN-6457 in Adult Participants With Symptomatic Prion Disease (PrD)).
ALT001
go.drugbank.com/drugs/DB33989ExperimentalALT001 is a biologic drug. ALT001 is under investigation in clinical trial NCT07833618 (A Phase II Study of ALT001 in Patients With Amyotrophic Lateral Sclerosis (ALS)).
Roxatidine acetate
go.drugbank.com/drugs/DB08806InvestigationalRoxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.
Categories: Heterocyclic Compounds, 1-RingProducts: NEOH 2Azilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigationalIt is also available in a combination product with [chlorthalidone]. … It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011.
Mixtures: EDARBI CLD®, EDARBI CLD® 40MG/12.5MGCategories: Angiotensin 2 Receptor Blocker, P-glycoprotein inhibitorsTetraethylammonium
go.drugbank.com/drugs/DB08837InvestigationalThe only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. … The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels.
Categories: MATE 1 Substrates, MATE 2 SubstratesSerotonin
go.drugbank.com/drugs/DB08839InvestigationalNutraceuticalFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Synonyms: 3-(2-Aminoethyl)-1H-indol-5-ol, 5-HTInternational brands: 5-HTP, Super 5-HTPEllagic acid
go.drugbank.com/drugs/DB08846InvestigationalEllagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement … of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Heterocyclic Compounds, 1-RingUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalA recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESMYA® 5 MG COMPRIMIDOS, เอสมายาชนิดเม็ด 5 มก.Fingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigational[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. … Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects.
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: DROPTON®, GENBIEMOD®