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Displaying results 671 - 680 of 10000 in total
  1. Drug

    Canakinumab

    go.drugbank.com/drugs/DB06168
    ApprovedInvestigational

    It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated.

    Products: ILARIS 150MG POWDER FOR SOLUTION FOR INJECTION, Ilaris Powder for Solution for Injection 150mg/vial
  2. Drug

    Clorazepic acid

    go.drugbank.com/drugs/DB00628
    ApprovedIllicit

    In September 2020, a black box warning describing these risks was included on the product label of benzodiazepines as per FDA regulation. … [L44798] Clorazepate and its active metabolite, nordiazepam, are present in breast milk.[A958,L44788]

    International brands: Gen-xeneProducts: Tranxene Cap 15mg, Novo-clopate Cap 15mg
  3. Drug

    Terbutaline

    go.drugbank.com/drugs/DB00871
    ApprovedInvestigational

    Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s and early 1970s. … [A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]

    Mixtures: BRICANYL EXProducts: TERBUTALINA 10MG / ML SOLUCION PARA NEBULIZACION, PHARMANIAGA TERBUTALINE RESPIRATOR SOLUTION 10MG/ML
  4. Drug

    Inotuzumab ozogamicin

    go.drugbank.com/drugs/DB05889
    ApprovedInvestigational

    [A20352] Inotuzumab ozogamicin was first approved by the European Commission in June 2017 for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). … Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin

    Products: BESPONSA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1MG/VIAL
  5. Drug

    Amodiaquine

    go.drugbank.com/drugs/DB00613
    ApprovedInvestigational

    A 4-aminoquinoquinoline compound with anti-inflammatory properties.

    Products: Sunoquine Tablet 100mg
  6. Drug

    Proguanil

    go.drugbank.com/drugs/DB01131
    Approved

    It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. … Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells.

    Mixtures: ATOVAQUONE E PROGUANILE SANDOZ, ATOVAQUONE E PROGUANILE MYLAN GENERICSProducts: Paludrine Tab 100mg
  7. Drug

    Cisatracurium

    go.drugbank.com/drugs/DB00565
    ApprovedInvestigational

    [A243416] Compared to atracurium, cisatracurium produces a lower degree of histamine release.[A253597] … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597].

    Products: Nimbex 10mg/ml, KABICURIUM® 10MG/5ML
  8. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type … Cardiovascular disease is the most common cause of death in these patients [A177083].

    Mixtures: Vokanamet (Canagliflozin 150mg/ Metformin 500mg) Film-Coated Tablet, Vokanamet (Canagliflozin 150mg/ Metformin 850mg) Film-Coated TabletCategories: Drugs Used in Diabetes
  9. Drug

    Abrocitinib

    go.drugbank.com/drugs/DB14973
    ApprovedInvestigational

    [A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. … including atopic dermatitis, a chronic inflammatory skin disease with complex pathogenesis.

    Products: CIBINQO® 100MG, Cibinqo 100mg Film-Coated Tablets
  10. Drug

    Etravirine

    go.drugbank.com/drugs/DB06414
    ApprovedInvestigational

    On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of adult HIV-1 infection documented to be resistant to therapy with other NNRTIs and antiretroviral … In 2013, reports of Autoimmune disorders (such as Graves’ disease, polymyositis, and Guillain-Barré syndrome) in the setting of immune reconstitution, as well as more in depth information about the development

    Products: INTELENCE TABLET 100MG