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Displaying results 671 - 680 of 10000 in total
  1. Drug

    5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB08741
    Experimental

    Synonyms: 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
  2. Drug

    4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol

    go.drugbank.com/drugs/DB03272
    Experimental

    Synonyms: 4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol
  3. Drug

    4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07531
    Experimental

    Synonyms: 4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE
  4. Drug

    Orotidylic acid

    go.drugbank.com/drugs/DB02957
    Experimental

    Synonyms: 6-carboxy-5'-uridylic acid, Orotidine 5'-phosphateCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Defactinib

    go.drugbank.com/drugs/DB12282
    ApprovedInvestigational

    Defactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … [L53198,L53208] FAK is important for the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, and its upregulation is a key

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
  6. Drug

    Oteseconazole

    go.drugbank.com/drugs/DB13055
    ApprovedInvestigational

    [L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. … [L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and little interaction with human cytochrome P450s.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, 2-Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl)-,(αR)
  7. Drug

    Dutasteride

    go.drugbank.com/drugs/DB01126
    ApprovedInvestigational

    It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland.

    Mixtures: DUODART 0,5 MG/0,4 MG KAPSÜL,7 KAPSÜL, Bakumokon 5% MinoxidilCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates
  8. Drug

    SB-409513

    go.drugbank.com/drugs/DB01793
    Experimental

    Synonyms: I-5
  9. Drug

    Tiliquinol

    go.drugbank.com/drugs/DB20266
    Experimental

    Tiliquinol is a small molecule drug. Tiliquinol has a monoisotopic molecular weight of 159.07 Da.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-methyl-8-quinolinol, 5-methylquinolin-8-ol
  10. Drug

    Vitamin B 12 factor IIIm

    go.drugbank.com/drugs/DB02667
    Experimental

    Synonyms: 5-Methoxybenzimidazole vitamin B12, 5-Methoxybenzimidazolylcobalamin