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Displaying results 6841 - 6850 of 10000 in total
  1. Drug

    Rupitasertib

    go.drugbank.com/drugs/DB15431
    Investigational

    M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).

  2. Drug

    Vevorisertib

    go.drugbank.com/drugs/DB21481
    Investigational

    Vevorisertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Vevorisertib is a serine/threonine kinase inhibitor. … Vevorisertib is under investigation in clinical trial NCT02761694 (Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations

  3. Drug

    SYNB1353

    go.drugbank.com/drugs/DB17666
    Investigational

    SYNB1353 is a strain of the probiotic bacteria _Escherichia coli_ (_E. coli_) type Nissle and an engineered probiotic drug. … It is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion into homocysteine.[L45983]

  4. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding immunoglobulin levels and 50% serum neutralizing titers higher than those observed in [COVID … [L15012] BNT162b1 is undergoing further evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701).

  5. Drug

    Isospaglumic acid

    go.drugbank.com/drugs/DB19650
    Investigational

    Isospaglumic acid is under investigation in clinical trial NCT06800274 (Clinical and Biological Evaluation of NAAGA Versus Azelastine Eye Drops in Allergic Subjects With Tear Film Dysfunction). … Isospaglumic acid has a monoisotopic molecular weight of 304.09 Da.

    Synonyms: N-acetylaspartylglutamic acid
  6. Drug

    Glovadalen

    go.drugbank.com/drugs/DB21709
    Investigational

    Glovadalen is under investigation in clinical trial NCT06970301 (A Study to Assess the Safety and Tolerability, and Pharmacokinetics of UCB0022 in Healthy Caucasian, Japanese, and Chinese Participants) … Glovadalen has a monoisotopic molecular weight of 475.14 Da.

  7. Drug

    Cintirorgon

    go.drugbank.com/drugs/DB20916
    Investigational

    Cintirorgon is a small molecule drug. Cintirorgon is under investigation in clinical trial NCT02929862 (Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer). … Cintirorgon has a monoisotopic molecular weight of 603.12 Da.

  8. Drug

    CoVac-1

    go.drugbank.com/drugs/DB16429
    Investigational

    Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588]. … It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults (pVAC))[L30428] and aims to induce broad

  9. Drug

    Chiauranib

    go.drugbank.com/drugs/DB16124
    Investigational

    Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).

  10. Drug

    Methscopolamine bromide

    go.drugbank.com/drugs/DB00462
    Approved

    A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.

    Synonyms: N-methylhyoscine bromide, N-methylscopolammonium bromide