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IO-202
go.drugbank.com/drugs/DB17548InvestigationalIO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.
Recombinant alpha 1-antitrypsin
go.drugbank.com/drugs/DB05481InvestigationalAlpha 1-antitrypsin is a glycoprotein primarily produced by hepatocytes, and to a lesser extent, immune system cells. … The proteinase/antiproteinase balance is believed to be important for maintaining healthy skin. The rAAT topical gel (Dermolastin™) is indicated for patients with atopic dermatitis and psoriasis.
Synonyms: Recombinant alpha 1-antitrypsinProducts: VENTIA®2%Enpatoran
go.drugbank.com/drugs/DB16501InvestigationalIt was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis
Synonyms: 5-((3R,5S)-3-AMINO-5-TRIFLUOROMETHYLPIPERIDIN-1-YL)QUINOLINE-8-CARBONITRILEFenbufen
go.drugbank.com/drugs/DB08981ApprovedFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. … It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast.
Synonyms: 4-(4-Biphenylyl)-4-oxobutyric acid, 3-(4-Phenylbenzoyl)propionic acidCategories: Non COX-2 selective NSAIDSRumex salicifolius var. mexicanus pollen
go.drugbank.com/drugs/DB10902ApprovedRumex salicifolius var. mexicanus pollen is the pollen of the Rumex salicifolius var. mexicanus plant. Rumex salicifolius var. mexicanus pollen is mainly used in allergenic testing.
Salix lucida ssp. lasiandra pollen
go.drugbank.com/drugs/DB10916ApprovedSalix lucida ssp. lasiandra pollen is the pollen of the Salix lucida ssp. lasiandra plant. Salix lucida ssp. lasiandra pollen is mainly used in allergenic testing.
Sorghum bicolor subsp. bicolor pollen
go.drugbank.com/drugs/DB10965ApprovedSorghum bicolor subsp. bicolor pollen is the pollen of the Sorghum bicolor subsp. bicolor plant. Sorghum bicolor subsp. bicolor pollen is mainly used in allergenic testing.
Sorghum bicolor subsp. drummondii pollen
go.drugbank.com/drugs/DB10966ApprovedSorghum bicolor subsp. drummondii pollen is the pollen of the Sorghum bicolor subsp. drummondii plant. Sorghum bicolor subsp. drummondii pollen is mainly used in allergenic testing.
Oxolinic acid
go.drugbank.com/drugs/DB13627InvestigationalCategories: Topoisomerase II Inhibitors, 4-QuinolonesNorflurane
go.drugbank.com/drugs/DB13116ApprovedInvestigationalWithdrawnNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates