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Displaying results 681 - 690 of 10000 in total
  1. Drug

    Zanamivir

    go.drugbank.com/drugs/DB00558
    ApprovedInvestigational

    A guanido-neuraminic acid that is used to inhibit neuraminidase.

    Synonyms: 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid, 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acidCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding.

    Synonyms: 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one, 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)International brands: Vepesid K
  3. Drug

    3-{[(2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2H-indol-2-one

    go.drugbank.com/drugs/DB08124
    Experimental

    Synonyms: 3-{[(2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2H-indol-2-one
  4. Drug

    5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE

    go.drugbank.com/drugs/DB06958
    Experimental

    Synonyms: 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
  5. Drug

    4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one

    go.drugbank.com/drugs/DB07824
    Experimental

    Synonyms: 4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one
  6. Drug

    Resmetirom

    go.drugbank.com/drugs/DB12914
    ApprovedInvestigational

    Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. … [L50336] Thyroid hormones directly regulate lipid metabolism in the liver; thus, impaired thyroid function, such as low serum thyroid hormone levels, is often observed in NAFLD.

    Synonyms: 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-, 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazine-6-carbonitrileCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Drug

    2'-deoxyuridine 5'-alpha,beta-imido-diphosphate

    go.drugbank.com/drugs/DB03641
    Experimental

    Synonyms: 2'-Deoxy-5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]uridine, 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate
  8. Drug

    Eluxadoline

    go.drugbank.com/drugs/DB09272
    ApprovedInvestigational

    Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system.

    Synonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acidCategories: mu-Opioid Receptor Agonist, Heterocyclic Compounds, 1-Ring
  9. Drug

    Cyclohexyl-pentyl-maltoside

    go.drugbank.com/drugs/DB04664
    Experimental

    Synonyms: CYMAL(R)-5, CYMAL-5
  10. Drug

    ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate

    go.drugbank.com/drugs/DB06906
    Experimental

    Synonyms: ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate