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Givastomig
go.drugbank.com/drugs/DB18618InvestigationalGivastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
ABBV-011
go.drugbank.com/drugs/DB18622InvestigationalABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Synonyms: an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicinCTX130
go.drugbank.com/drugs/DB18627InvestigationalCTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Synonyms: Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigenNerispirdine
go.drugbank.com/drugs/DB12714InvestigationalNerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMSX-122
go.drugbank.com/drugs/DB12715InvestigationalMSX-122 has been used in trials studying the treatment of Solid Tumors.
Categories: Heterocyclic Compounds, 1-RingTurofexorate isopropyl
go.drugbank.com/drugs/DB12719InvestigationalFxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRO-5028442
go.drugbank.com/drugs/DB12721InvestigationalRO5028442 has been used in trials studying Autistic Disorder.
Categories: Heterocyclic Compounds, 2-RingAZD-7295
go.drugbank.com/drugs/DB12724InvestigationalAZD7295 has been investigated for the treatment of Hepatitis C.
Dipraglurant
go.drugbank.com/drugs/DB12733InvestigationalIt is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).
Categories: Heterocyclic Compounds, 1-RingCGI-1842
go.drugbank.com/drugs/DB12744InvestigationalJI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.
Categories: Heterocyclic Compounds, 2-Ring