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Displaying results 6911 - 6920 of 10000 in total
  1. Drug

    Emzeltrectinib

    go.drugbank.com/drugs/DB21605
    Experimental

    The usage of the INN stem '-trectinib' in the name indicates that Emzeltrectinib is a tropomyosin receptor kinase (TRK) inhibitor. Emzeltrectinib has a monoisotopic molecular weight of 376.13 Da.

  2. Drug

    Zavondemstat

    go.drugbank.com/drugs/DB21608
    Experimental

    The usage of the INN stem '-demstat' in the name indicates that Zavondemstat is a Lysine-specific histone demethylase inhibitor. Zavondemstat has a monoisotopic molecular weight of 431.22 Da.

  3. Drug

    NOX-700

    go.drugbank.com/drugs/DB05464
    Experimental

    It has since been found that oxidative signaling of the redox-sensitive transcription factor, NF-κB, and inhibiting protein glycation are responsible for the drug's therapeutic effects. … In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin.

  4. Drug

    CMLVAX100

    go.drugbank.com/drugs/DB05164
    Experimental

    CMLVAX100 is a vaccine targeting the BCR-ABL-derived p210 fusion protein which reduces residual disease in some patients with chronic myeloid leukemia.

  5. Drug

    Funapide

    go.drugbank.com/drugs/DB11769
    Investigational

    Funapide has been used in trials studying the treatment of Pharmacokinetics, Postherpetic Neuralgia, and Osteoarthritis of the Knee.

  6. Drug

    Gallium maltolate

    go.drugbank.com/drugs/DB05420
    Investigational

    Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.

  7. Drug

    Azelnidipine

    go.drugbank.com/drugs/DB09230
    Investigational

    Azelnidipine is a dihydropyridine calcium channel blocker. It is marketed by Daiichi-Sankyo pharmaceuticals, Inc. in Japan. It has a gradual onset of action and produces a long-lasting decrease in blood pressure, with only a small increa...

  8. Drug

    AdimrSC-2f

    go.drugbank.com/drugs/DB16436
    Investigational

    A phase I study (NCT04522089) will investigate the safety and immunogenicity of the vaccine[L30553, L30548]. … The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553].

  9. Drug

    Imnopitant

    go.drugbank.com/drugs/DB21456
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1​ (substance P) receptor antagonist. Imnopitant has a monoisotopic molecular weight of 550.22 Da.

  10. Drug

    Libvatrep

    go.drugbank.com/drugs/DB21488
    Experimental

    The usage of the INN stem '-vatrep' in the name indicates that Libvatrep is a transient receptor potential vanilloid (TRPV) antagonist. Libvatrep has a monoisotopic molecular weight of 305.12 Da.