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Irampanel
go.drugbank.com/drugs/DB21123InvestigationalIrampanel is a small molecule drug. … Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).
Itruvone
go.drugbank.com/drugs/DB21543InvestigationalItruvone is a small molecule drug. Itruvone is under investigation in clinical trial NCT02322086 (A Phase 2 Study of Cellular and Immunologic Changes in the Skin of Subjects Receiving PH-10). … Itruvone has a monoisotopic molecular weight of 296.21 Da.
Synonyms: Pregn-4-en-20-yn-3-oneTaragarestrant
go.drugbank.com/drugs/DB21574InvestigationalTaragarestrant is under investigation in clinical trial NCT06954961 (A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer). … Taragarestrant is a small molecule drug.
Cambinol
go.drugbank.com/drugs/DB15493ExperimentalCambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival under stress. This activity is currently being investigated for its use as a cancer treatment.
Fluprednidene
go.drugbank.com/drugs/DB08970ExperimentalFluprednidene is a corticosteroid.
Categories: Corticosteroids, Moderately Potent (Group II)Furazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approvedA nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimineNasoVAX
go.drugbank.com/drugs/DB15859InvestigationalNasoVAX contains replication-deficient adenovirus vectors in suspension. It is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells[L16313]. … As of June 2020, NasoVAX is being evaluated in a Phase 2 clinical trial for safety and effectivness in preventing worsening symptoms in hospitalized COVID-19 patients (NCT04442230).
Mesterolone
go.drugbank.com/drugs/DB13587InvestigationalIt is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. … Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH [A27177, A27178].
Solabegron
go.drugbank.com/drugs/DB06190InvestigationalSolabegron (GW-427,353) is a selective β3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.