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TOL-101
go.drugbank.com/drugs/DB16980InvestigationalSynonyms: Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptorTrastuzumab duocarmazine
go.drugbank.com/drugs/DB16342InvestigationalTrastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsBecotatug
go.drugbank.com/drugs/DB19069InvestigationalJMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor
Synonyms: Jmt101 (fully human monoclonal igg1 antibody targeting epidermal growth factor receptor (egfr)), Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimerIbutilide
go.drugbank.com/drugs/DB00308ApprovedIt is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR).
EDI-200
go.drugbank.com/drugs/DB18188InvestigationalEDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Synonyms: HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEINBoserolimab
go.drugbank.com/drugs/DB17452InvestigationalSynonyms: Immunoglobulin G1-kappa, anti-(homo sapiens CD27 (TNFRSF7, tumor necrosis factor receptor (TNFR) superfamily member 7))Olinvacimab
go.drugbank.com/drugs/DB16265InvestigationalOlinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Synonyms: Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2, Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac-0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimerVonlerolizumab
go.drugbank.com/drugs/DB16352InvestigationalVonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Ar...
Synonyms: Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 heavy chain (1-447), Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibodySTM-217
go.drugbank.com/drugs/DB17358ExperimentalSynonyms: Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a