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CTB001
go.drugbank.com/drugs/DB18316InvestigationalCTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.[L48146]
LAVA-051
go.drugbank.com/drugs/DB18395InvestigationalLAVA-051 is a humanized Vγ9Vδ2-T cell-engaging bispecific antibody.
ISB 2001
go.drugbank.com/drugs/DB18570InvestigationalISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
BG1805
go.drugbank.com/drugs/DB18667InvestigationalBG1805 is an investigational anti-CLL1 chimeric antigen receptor (CAR) T-cell therapy.
Rovaleucel
go.drugbank.com/drugs/DB18691InvestigationalRovaleucel is an EBV-specific autologous T-cell therapy under investigation for the treatment of EBV-positive cancers.
NNC-55-0396 free base
go.drugbank.com/drugs/DB17037ExperimentalNNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047]
Gemogenovatucel-T
go.drugbank.com/drugs/DB17412Investigational[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Synonyms: Gemogenovatucel-TErfonrilimab
go.drugbank.com/drugs/DB17446InvestigationalErfonrilimab is a bispecific monoclonal antibody directed against both the programmed cell death-1 ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA4).
UCART22
go.drugbank.com/drugs/DB17466InvestigationalUCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.
Synonyms: Allogeneic gene-edited CAR T cells UCART22, Allogeneic TALEN gene-edited CAR T-Cells UCART22CB-010
go.drugbank.com/drugs/DB17711InvestigationalCB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.[L46158]