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Evofosfamide
go.drugbank.com/drugs/DB06091InvestigationalTH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. … TH-302 is a novel cancer therapeutic specifically activated under the low oxygen or "hypoxic" conditions typical of solid tumor cancer cells.
Emoxypine
go.drugbank.com/drugs/DB19172InvestigationalEmoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure).
Categories: Compounds used in a research, industrial, or household settingRolofylline
go.drugbank.com/drugs/DB12670InvestigationalRolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
Irsogladine
go.drugbank.com/drugs/DB13056InvestigationalIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Categories: Compounds used in a research, industrial, or household settingVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnVinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Synonyms: 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine, 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastineCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexKetanserin
go.drugbank.com/drugs/DB12465InvestigationalKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDiaziquone
go.drugbank.com/drugs/DB17174ExperimentalCategories: Compounds used in a research, industrial, or household settingPhosphocysteamine
go.drugbank.com/drugs/DB17640ExperimentalCategories: Compounds used in a research, industrial, or household settingPhosphonothreonine
go.drugbank.com/drugs/DB02482ExperimentalThe phosphoric acid ester of threonine. Used as an identifier in the analysis of peptides, proteins, and enzymes. [PubChem]
ATL1101
go.drugbank.com/drugs/DB05023ExperimentalATL1101 is being developed as a cream for the topical treatment of mild to moderate cases of psoriasis. … ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis.