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Hycanthone
go.drugbank.com/drugs/DB14061ExperimentalPotentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingSynonyms: 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-oneNesvategrast
go.drugbank.com/drugs/DB19337InvestigationalNesvategrast is under investigation in clinical trial NCT05409235 (Nesvategrast (OTT166) in Diabetic Retinopathy (DR)).
Synonyms: (s)-3-(6-(difluoromethoxy)pyridin-3-yl)-3-(oxo-2-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoate, 3-Pyridinepropanoic acid, 6-(difluoromethoxy)-β-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]-, (βS)-AP-101
go.drugbank.com/drugs/DB17947InvestigationalAP-101 is a recombinant human antibody directed against human misfolded superoxide dismutase 1.
ARGX-119
go.drugbank.com/drugs/DB18133InvestigationalARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSKSatricabtagene autoleucel
go.drugbank.com/drugs/DB18288InvestigationalSatricabtagene autoleucel is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).
ISB 2001
go.drugbank.com/drugs/DB18570InvestigationalISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
ISTH0036
go.drugbank.com/drugs/DB18606InvestigationalISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA
BVX-001
go.drugbank.com/drugs/DB18733ExperimentalBVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
AZD-7268
go.drugbank.com/drugs/DB19203InvestigationalAZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Benzamide, n-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-, N-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-benzamideOXB-301
go.drugbank.com/drugs/DB19269InvestigationalOXB-301 is under investigation in clinical trial NCT00397345 (Trovax Renal Immunotherapy Survival Trial).